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Glucosamine (n-acetylglucosamine) in capsules

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Regular price 19,95€ i.e. 0,66€ / capsule
Sale price / Kg 19,95€ Regular price / Kg i.e. 0,66€ / capsule
  • 100 % pure
  • Preservation of joint health
  • Treatment of pain -related pain
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Not recommended for pregnant and breastfeeding women and children, diabetic or pre-diabetic, asthmatic or treated by anti-vitamin K, people with food allergy to crustaceans or insects, people whose food is controlled For sodium, potassium or calcium. Not recommended for people with food allergy to crustaceans or insects.

Take 1 capsule per day during a meal.

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12:00

During lunch

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Kéto Sans biotiques Sans caséine Sans gluten Sans lactose

Glucosamine is the main molecule capable of ensuring the right joint recovery, as it accelerates the body's ability to make glycosaminoglycans and hyaluronic acid.

Glucosamine is a precursor of gags, the second component of cartilages, tendons and ligaments, after collagen. Our body naturally produces its glucosamine from sugar and an amino acid: glutamine.

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N-acetylglucosamine

KANEKA

Glucosamine is a pioneer of gags, the second component of cartilages, tendons and ligaments, after collagen.

Bovin capsules

SUHEUNG

 

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  • Take 1 capsule per day during a meal.

    Learn more

    12:00

    During lunch

  • Kéto Sans biotiques Sans caséine Sans gluten Sans lactose

    Glucosamine is the main molecule capable of ensuring the right joint recovery, as it accelerates the body's ability to make glycosaminoglycans and hyaluronic acid.

    Glucosamine is a precursor of gags, the second component of cartilages, tendons and ligaments, after collagen. Our body naturally produces its glucosamine from sugar and an amino acid: glutamine.

  • N-acetylglucosamine

    KANEKA

    Glucosamine is a pioneer of gags, the second component of cartilages, tendons and ligaments, after collagen.

    See all the ingredients

What the product does

What the product does

What the product does

Acceleration of the joint recovery process

N-acetylglucosamine accelerates the anabolism of cartilages so joint recovery. Research shows that the N-acetylglucosamine increases the speed of cartilage regeneration by 40 %.

Anti -wrinkle effect

By ensuring elasticity and hydration, the N-acetylglucosamine acts as an anti-wrinkle, because the latter are due to the dryness of the skin and its lack of elasticity.

to have more details on the Profits of the N-acetylglucosamine, you can consult the game more information more.



1. Carbohydrates participate in the recovery of muscular functions (contraction) after a very intense and/or long -term physical effort that caused muscle fatigue and the exhaustion of glycogen stocks in the skeletal muscles. The benefits are obtained by consuming carbohydrates from all sources, with a total intake of 4 g per kg of body weight per dose within 4 hours, and at the latest within 6 hours of a very intense physical effort and/or Long -term having resulted in muscle fatigue and the exhaustion of glycogen stocks in the skeletal muscles.

2. Carbohydrates are an energy source during the effort.

3. Proteins contribute to the development and maintenance of muscle mass.

Composition

Everything about this product

Interaction with other Nutrimuscle products

  • No known immediate synergy.

  • No negative interaction known with other supplements.

References

  • (1) Kessler M.A. Volume Changes in the menisc and articular cartilage of runners: an in vivo investigation based on 3-d magnetic imaging. Am J Sports Med. 2006 May; 34 (5): 832-6. (2) Poolsup N., et al. Glucosamine Long-Term Treatment and the Progression of Knee Osteoarthritis: Systematic Review of Randomized Controlled Trials. Ann Pharmacother. 2005 Jun; 39 (6): 1080-7. (3) REGINSTER J.Y. Long-Term Effects of Glucosamine Sulphate On Osteoarthritis Progression: A RANDOMISED, PLACEBO-CONTROLLED CLINICAL TRIAL. Lancet 2001 Jan 27; 357: 251-56. (4) Ostojic sm. Glucosamine Administration in Athletes: Effects on Recovery of Acute Knee Injury. RES SPORTS MED. 2007 APR-Jun; 15 (2): 113-24. (5) Yoshimura M. Evaluation of the Effect of Glucosamine Administration On Biomarkers for Cartilage and Bone Metabolism in Soccer Players. Int j mol med. 2009 Oct; 24 (4): 487-94. (6) Shmidt ei. [Long-Term Efficacy and Safety of Chondroitin Sulphate (Structum, France) in Patients with coxarthosis]. TER Arkh. 2007; 79 (1): 65-7. (7) Vangsness CT JR. A Review of Evidence-Based Medicine for Glucosamine and Chondroitin Sulfate uses in Knee osteoarthritis. Arthroscopy. 2009 Jan; 25 (1): 86-94. (8) Bell GA. Use of glucosamine and chondroitin in relationship to mortality. EUR J Epidemiol. 2012 Jul 25. [Epub Ahead of Print] (9) Brasky TM. Use of glucosamine and chondroitin and lung cancer risk in the vitamins and lifestyle (vital) cohort. Cancer Causes Control. 2011 Sep; 22 (9): 1333-42. EPUB 2011 Jun 25. (10) Zhang YX. Effects of Chondroitin Sulfate and Glucosamine in Adult Patients With Kaschin-Beck Disease. Rheumatol clin. 2010 APR; 29 (4): 357-62. (11) Tat SK. Chondroitin and glucosamine sulfate in Combination Decrease the Pro-Resorptive Properties of Human Osteoarthritis Subchondral Bone Osteoblasts: A Basic Science Study. Arthritis Res ther. 2007; 9 (6): R117. (12) Lippielo L. Collagen Synthesis in Tenocytes, Ligament Cells and Chondrocytes Exposed to A Combination of Glucosamine Hcl and Chondroitin Sulfate. EVID BASED COMPLEMENT ALTERNAT MED. 2007 Jun; 4 (2): 219-24. (13) Calamia V. Pharmacoproteomic Study of the Effects of Chondroitin and Glucosamine Sulfate On Human Articular Chondrocytes. Arthritis Research & Therapy 2010, 12: R138; (14) Clegg do.glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med. 2006 Feb 23; 354 ??(8): 795-808. (15) Jerosch J. Effects of Glucosamine and Chondroitin Sulfate On Cartilage Metabolism in OA: Outlook on other nutrients Especially Omega-3 Fatty Acids. Int j rheumatol. 2011; 2011: 969012. (16) CALAMIA V. Secretome Analysis of Chondroitin Sulfate-Treeated Chondrocytes Reveals ITS Anti-Angiogenic, Anti-inflammatory and anti-catabolic properies. Arthritis Research & Therapy 2012, 14: R202. (17) Burton AF. Decreased Incorporation of 14C-Glucosamine Relative to 3H-N-Acétyl-Glucosamine in the intestinal mucosa of patients with inflammatory bowel disease. AM J gastroenterol. 1983 Jan; 78 (1): 19-22. (18) Goodman MJ. Glucosamine Synthetase Activity of the Colonic Mucosa in Ulcerative Colitis and Crohn's Disease. GUT, 1977, 18, 219-229 (19) Auricchio S. Mannan and Oligomers of N-Acetylglucosamine Protect Intestinal Mucosa of Celiac patients with Active Disease from in vitro toxicity of gliadin peptides. Gastroenterology. 1990 Oct; 99 (4): 973-8. (20) Rhodes JM. Unifying hypothesis for inflammatory bowel disease and associated colon cancer: Sticking the pieces Together with sugar. Lancet 1996; 347: 40. (21) Salvatore S. A Pilot Study of N-Acetyl Glucosamine, A Nutritional substrate for glycosaminoglycan synthesis, in Paediatric Chronic Inflammatory Bowel Disease. Pharmacol therrin food. 2000 DEC; 14 (12): 1567-79. (22) Bak YK. Effects of Dietary Supplementation of Glucosamine Sulfate On Intestinal Inflammation in A Mouse Model of Experimental colitis. J gastroenterol hepatol. 2014 May; 29 (5): 957-63. (23) Yomogida S. Glucosamine, A Naturally Occurring Amino Monosaccharide, suppresses Dextran sulfate sodium-induced colitis in rats. Int j mol med. 2008 Sep; 22 (3): 317-23. (24) Kantor Ed. Use of Glucosamine and Chondroitin Supplements and Risk of Colorectal Cancer. Cancer Causes Control. 2013 Jun; 24 (6): 1137-46 (25) Masuda S. Anti-T-Tomor Properties of Orally Administered Glucosamine and N-Acetyl-D-Glucosamine Oligomers in A Mouse Model. Carbohydr polym. 2014 Oct 13; 111: 783-7. (26) Jung CW. Anti-cancer Properties of Glucosamine-Hydrochloride in YD-8 Human Oral Cancer Cells: Induction of the Caspase Dependent Apoptosis and Down-Regulation of HIF-1?. Toxicol in vitro. 2012 Feb; 26 (1): 42-50. (27) Brasky TM. Use of glucosamine and chondroitin and lung cancer risk in the vitamins and lifestyle (vital) cohort. Cancer Causes Control. 2011 Sep; 22 (9): 1333-42. (1) Uitterlinden ej. Glucosamine reduces anabolic as well as catabolic processes in bovine chondrocytes cultural in alginate. Osteoarthritis cartilage. 2007 Nov; 15 (11): 1267-74. (2) Uitterlinden ej. Glucosamine Decreeses Expression of Anabolic and Catabolic Genes in Human Osteoarthritic Cartilage Explants. Osteoarthritis cartilage. 2006 Mar; 14 (3): 250-7. (3) Shikhman a R. Chondroprotective Activity of N-Acetylglucosamine in Rabbits with Experimental osteoarthritis. Ann Rheum Dis 2005; 64: 89-94 (4) Grevenstein J. Cartilage Changes in Rats induced by papain and the influence of Treatment with n-acetylglucosamine. ACTA ORTOIPAEDICA Belgica 1991, Vol. 57, No2, pp. 157-161 (5) Talent JM. Pilot Study of Oral Polymeric N-Acetyl-D-Glucosamine AS A Potential Treatment for Patients With Osteoarthritis. Clin Ther. 1996 Nov-Dec; 18 (6): 1184-90. (6) Tamai Y. Enhanced Healing of Cartilaginous Injuries by n-acetyl-d-glucosamine and glucuronic acid. Carbohydrate Polymers Volume 54, Issue 2, 1 November 2003, pages 251–262 (7) Serpi M. Novel Phosphoramidate Prodrugs of N-Acetyl- (D) -Glucosamine with Antidegenerative Activity on Bovine and Human Cartilage Explain. J Med Chem. 2012 May 24; 55 (10): 4629-39. (8) McGuigan C. Phosphate Prodrugs derived from n-acetylglucosamine have enhanced chondroprotective Activity in Explant Cultures and replant at New Lead in Antiosteoarthritis Drug Discovery. J Med Chem. 2008 Sep 25; 51 (18): 5807-12. (9) Shikhman ar. N-acetylglucosamine presence IL-1ß-Mediated Activation of Human Chondrocytes. The Journal of Immunology April 15, 2001 vol. 166 no. 8 5155-5160 (10) Setnikar I. Absorption, Distribution and Excretion of Radioactivity after a single IV or oral administration of [14c] to the rat. Pharmatherapeutica (1984) 3: 538-550 (11) Shoji A. Metabolic Layout of [14C] N-acetylglucosamine in rats. Chitin and Chitosan Research (1999) 5 (1): 43-42. (12) Kyoung-Youl L. Subchronic Toxicity Study of Dietary N-Acetylglucosamine in F344 Rats. Food and Chemical Toxicology Volume 42, Issue 4, April 2004, pages 687–695 (13) Miwa T. Lack of Chronic Toxicity or Carcinogenicity of Dietary N-Acetylglucosamine in F344 Rats. Food and Chemical Toxicology Volume 47, Issue 2, February 2009, pages 462–471 (14) Chen JK. N-acetylglucosamine: production and applications. Mar. Drugs 2010, 8 (9), 2493-2516 (15) Salvatore S. A Pilot Study of N-Acetyl Glucosamine, A Nutritional substrate for glycosaminoglycan synthesis, in Paediatric Chronic Inflammatory Bowel Disease. Food pharmacology & therapeutics volume 14, outlet 12, pages 1567–1579, December 2000 (16) Sayo T. Synergestic effect of n-acetylglucosamine and retinoids on hyaluronan production in Huma (17) Tu cx. Exogesnous n-acetylglucosamine Increases Hyaluronan Production in Culture Human Dermal Fibroblasts. Archives of Dermatological Research Volume 301, Number 7 (2009), 549-551.N Keratinocytes. Skin Pharmacol Physiol 2004; 17: 77–83 (18) Chen HR. Effect of different concentrations of Collagen, ceramides, n-acetyl glucosamine, or their mixture on enhancing the proliferation of keratinocytes, fibroblasts and the secretion of collagen and/or the expression of mrna of type I collagen. Journal of Food and Drug Analysis, vol. 16, No. 1, 2008, pages 66-74 (19) Kikuchi K. Oral N-acetylglucosamine Improves Skin Conditions of Female Volunteers: Clinical Evaluation by A Microscopic Three-Dimensal Skin Skin Analyzer Journal of Applied Cosmetology 2002, Vol. 20, No2, pp. 143-152 (20) Reyes E. Developments in Photoaging: Review of N-acetylglucosamine. Piel. 2011 (in Press) (21) Mammone T. The Effect of N-Acetyl-Glucosamine on Stratum Corneum Desquamation and water content in Human Skin. International Journal of Cosmetic Science. Volume 32, Issue 3, page 234, June 2010. (22) Hwang yp. N-acetylglucosamine suppressing collagenases Activation in ultraviolet B-Irradiated Human Dermal Fibroblasts: Involve of Calcium Ions and Mitogen-Activated Protein Kinases. Journal of Dermatological Science Volume 63, Issue 2, August 2011, pages 93–103. (23) Mkhikian H. Genetics and the Environment Converge to Dysregulate N-Glycosylation in Multiple Sclerosis. Nature Communications 2011. 2, article Number: 334

Learn more

  • In test tube, glucosamine is above all capable of inhibiting the degradation of existing joint cartilages and acts as a natural anti-inflammatory. It promotes lubrication and articular "nutrition" by stimulating the production of hyaluronic acid. There are several forms of glucosamine: glucosamine sulfate, glucosamine chlorhydrate, N-acetylglucosamine. What is the best?

Glucosamine benefits

  • As we have just seen, conventional glucosamines are especially effective in slowing down the processes of joint degeneration. But, what the sportsman is looking for above all is not to reduce the pace of joint degradation is an additional supplement that accelerates the regeneration of cartilages, therefore joint anabolism, in order to recover more quickly between two training sessions.

  • What makes the superiority of N-acetylglucosamine over other forms of glucosamine, is that N-acetylglucosamine is the direct precursor of glycosaminoglycans and hyaluronic acid. Classic glucosamines are only indirect precursors which must, first of all, be converted into N-acetylglucosamine before serving as a raw material for gags and hyaluronic acid. This conversion being very limiting, it explains why N-acetylglucosamine is more effective than glucosamine.

    therefore is not only in joints that N-acetylglucosamine Nutrimuscle plays an important role. N-acetylglucosamine Nutrimuscle also has vital skin functions. By ensuring elasticity and hydration, the N-acetylglucosamine Nutrimuscle acts as an anti-wrinkle, because the latter are due to the dryness of the skin and its lack of elasticity.

    for example, for 60 days, women received 1 g of N-acetylglucosamine orally daily. Their skin has become less oily, but benefits from a much better hydration which results in a visual improvement in the appearance of the face (19).

    the reduction of the oily appearance of the skin as well That its best hydration suggest that the N-acetylglucosamine could also help clean the skin of its impurities and therefore fight acne. It can also help healing, fight against excessive scrums and the harms of the sun on the skin (20-21-22).


    the N-acetylglucosamine also offers protection against cerebral degeneration (23) .



    1. The carbohydrates participate in the recovery of muscle functions (contraction) after a very intense and/or long -term physical effort that caused muscle fatigue and exhaustion of stocks glycogen in skeletal muscles. The benefits are obtained by consuming carbohydrates from all sources, with a total intake of 4 g per kg of body weight per dose within 4 hours, and at the latest within 6 hours of a very intense physical effort and/or Long duration having resulted in muscle fatigue and the depletion of glycogen stocks in skeletal muscles.

    2. Carbohydrates are a source of energy during effort.

    3. The proteins contribute to the development and maintenance of muscle mass.

Who is the product for?

  • N-acetylglucosamine Nutrimuscle is addressed:

    to athletes who wish to prevent injuries, especially for force sports practitioners such as athletic force or bodybuilding, because heavy loads and repetitions Movements damage their joints. High impact sports athletes such as mountain biking or running also request their joints and have a profit to supplement to n-acetylglucosamine nutrimuscle;
    to sedentary people who suffer from joint pain and wish to improve the comfort of their joints.

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