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Citrulline is an amino acid that has become an essential supplement for athletes and fitness enthusiasts concerned about their cardiovascular health. It plays a crucial role in nitric oxide synthesis and blood circulation, offering benefits ranging from improved physical performance to promoting better blood vessel health.
What is L-citrulline?
L-citrulline is a semi-essential non-protein amino acid. Citrulline is said to be non-protein because, unlike other common amino acids, food does not provide citrulline.
Only watermelon provides a little (about 1 g per kilo). As a result, all our citrulline must be synthesized from the intestinal breakdown of various other amino acids like glutamine and arginine. In return, in the kidneys, citrulline is massively converted into arginine.
What are the effects of citrulline?
Citrulline can be used for its anabolic action, for its health benefits, or as a sexual booster.
NO booster
Citrulline intake increases arginine levels in the same way as direct L-arginine intake. Indeed, part of an arginine supplementation is degraded during digestion, which is not the case for citrulline. The latter benefits from almost perfect absorption.
Following oral intake, urinary losses of citrulline are minimal, which proves that the body's absorption and retention capacities are excellent, even at high doses. Thus, 3 to 6 g of citrulline can double the level of arginine in the blood.
As citrulline promotes blood circulation during exercise, it will play a cardioprotective role during a sports event.
This property of citrulline gives it the status of an indirect but very effective booster of NO (nitric oxide) production. NO is a gas, produced by blood vessels, that facilitates circulation in the muscles, which increases their oxygenation and congestion. These two properties of citrulline explain why it is used both as a pre-workout booster and as a sexual booster, especially in synergy with arginine.
Sexual booster
Our sexual capabilities are closely linked to NO production. Citrulline is therefore perfectly capable of remedying deficiencies or even boosting sexual endurance in men who do not suffer from erectile dysfunction. For example, in men suffering from erectile dysfunction, daily intake of 1.5 g of citrulline allows 50% of users to regain a normal erection (compared to 8% in those using a placebo).
Cardiovascular and immune health
In cardiac patients, oral intake of 3 g of citrulline per day proves to be very effective in improving blood circulation. In healthy seniors, daily oral intake of 5.6 g of citrulline helps to "rejuvenate" their cardiovascular system.
In healthy young men, 6 g of citrulline helps the cardiovascular system better cope with cold-induced stress.
Citrulline is an important amino acid for maintaining human immune activity.
Usage tips
The short half-life of citrulline in the blood suggests that this amino acid should be used at least twice a day (2 capsules in the morning + 2 capsules in the evening) in order to achieve a constant elevation in the blood and thus increase the anabolic response to training and/or sexual prowess.
If you are only looking for congestion, Nutrimuscle L-citrulline base can be used, if possible with Nutrimuscle L-arginine base, one hour before sports or sexual activity, at a dose of 4 capsules at once.
While some people respond quickly to the vasodilating effects of citrulline, this is not the case for everyone. It takes 3 weeks of daily use of Nutrimuscle L-citrulline base to determine the individual effectiveness of this amino acid, particularly as a sexual booster.

